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KMID : 0605720080140020213
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Journal of the Korean Society of Biological Therapies in Psychiatry
2008 Volume.14 No. 2 p.213 ~ p.215
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A Case of Olanzapine Treatment in Patient with Cyclosporine-Induced Manic Symptoms
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Lee San-Soo
Lee Sang-Yeol
Hong Jeong-Wan
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Abstract
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We present the case of a 43-year-old woman with no previous diagnosis of bipolar disorder who underwent kidney transplantation for end stage renal disease. 7 years post-transplant, she exhibited manic symptoms including hyperactivity, elated mood, decreased need for sleep, grandiose and religious delusion, and pressured speech. Most reports about treatment of postoperative psychiatric problem-especially corticosteroid induced mood disor-der-have emphasized the use of Lithium, typical antipsychotics. We found a few case reports in which atypical antipsychotics were prescribed for those case but there is no one in which olanzapine was prescribed in a kidney transplanted patient.
Olanzapine is an atypical anti psychotics which has antimanic and mood-stabilizing as wall as sedative properties. And we reasoned that this agent might be useful for the treatment of mania in a kidney transplanted patient who is taking cyclosporine, and we report a case that the olanzapine treatment was successful in the transplanted patient with manic episode.
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KEYWORD
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Kidney transplantation, Cyclosporine, Mania, Olanzapine
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